This paper aims to explain the inequality and imbalance in the developmental levels of 6 selected cities in North Khorasan. The paper seeks to answer these two questions as to whether the spatial and non-spatial indices in regional disparities have an effect on equality? And can we achieve a functional model based on the evaluation of indicators? In order to achieve the goal and the answer to the question, indicators have been selected based on the importance and effects of the factors in both natural and human aspects. The method of this research is descriptive-analytical in nature and in terms of access to the facts of the descriptive-survey type and in terms of The purpose is to apply. Data analysis was performed using SPSS software and multi-criteria and cellular analysis using the coefficient of variation formula. Thus, the coefficient (from one to another) was determined in each case, the influential elements and the prestigious countries of inequality. The results show that the city of Bojnourd with a coefficient of 90 channels in North Khorasan has been used for structural changes by providing data matrices and presenting maps (with the help of GIS), and the most change coefficient is related to the percentages of urban population percentages. Other results of the study indicate that according to the coefficient of variation and determination of z in the cities of North Khorasan province, Bojnourd city has the first rank in 6 indexes of 10 selected indexes and its z value is 8.57 and the clear distance with Shirvan is The title of the second city is with a z = -3.54. The final finding of this research is modeling in the structural-functional changes and changes in North Khorasan which was proposed at the end of the paper.